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Friday 21 October 2022

Psilocybin and cancer

 Psilocybin and Cancer


Psilocybin is a psychoactive compound found in certain species of mushrooms, commonly known as "magic mushrooms."

Research suggests that psilocybin may have therapeutic potential in treating various mental health conditions, including depression, anxiety, and PTSD.

While there's limited direct research on psilocybin's effects on cancer, some studies have explored its potential benefits in palliative care and end-of-life anxiety among cancer patients.

A study published in the Journal of Psychopharmacology found that a single dose of psilocybin significantly reduced depression and anxiety in cancer patients, with effects lasting up to six months.

Another study published in the same journal reported that psilocybin-assisted therapy improved emotional and spiritual well-being in patients with advanced-stage cancer.


Psilocybin is believed to work by modulating serotonin receptors in the brain, leading to alterations in perception, mood, and cognition.

The psychedelic experience induced by psilocybin may help patients confront existential and emotional distress associated with cancer diagnosis and treatment.

Some cancer patients report profound mystical or spiritual experiences during psilocybin-assisted therapy, which can lead to greater acceptance and peace regarding their condition.

Psilocybin therapy is typically administered in a controlled setting under the supervision of trained professionals to ensure safety and optimize therapeutic outcomes.

While psilocybin shows promise in improving quality of life for cancer patients, more research is needed to fully understand its long-term effects and potential risks, especially regarding interactions with existing medications and medical conditions.


It's important to note that psilocybin is still classified as a Schedule I controlled substance in many countries, including the United States, which limits its availability for research and clinical use.

Despite regulatory challenges, there's growing interest in exploring the therapeutic potential of psilocybin and other psychedelics in various medical and mental health applications, including cancer care.

Advocates argue that psilocybin therapy represents a paradigm shift in how we approach mental health and end-of-life care, emphasizing holistic and patient-centered approaches.

Some researchers are investigating the potential anti-inflammatory and immunomodulatory effects of psilocybin, which could have implications for cancer treatment and symptom management. Learn more about psilocybin therapy at legal retreats like these in Jamaica here.

The psychedelic experience induced by psilocybin may also promote neuroplasticity and enhance psychological resilience, which could be beneficial for cancer patients coping with the challenges of diagnosis and treatment.


Psilocybin therapy is often integrated into a comprehensive treatment plan that may include conventional medical interventions, psychotherapy, and complementary therapies to address the multifaceted needs of cancer patients.

The therapeutic effects of psilocybin are not solely attributable to the compound itself but also to the therapeutic relationship, setting, and intentionality of the therapeutic experience.

Research on psilocybin and cancer is still in its early stages, and future studies will help elucidate its mechanisms of action and therapeutic potential in oncology.

It's essential for healthcare providers to have open and informed discussions with patients about the potential benefits, risks, and legal considerations of psilocybin therapy, allowing patients to make informed decisions about their care.

Integrating psilocybin therapy into mainstream healthcare will require overcoming regulatory hurdles, stigma, and cultural biases surrounding psychedelics and mental health treatment.


In February, 2023, there was a legal retreat for psilocybin facilitators. It was held in Jamaica. If you're interested, here's more info:

https://mobile.twitter.com/JACCRIorg/status/1583503287717797897 



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